Impedance levels vary (32 Ohm±15% vs 32 ohm), which can affect compatibility and audio output when used with different devices. The frequency response differs (20 Hz - 20000 Hz vs 20Hz - 40KHz), which can influence how well the headphones reproduce lows, mids, and highs. There is a noticeable difference in weight (63.5 Gm vs 51.33 GM), which may affect comfort during extended use. The driver size differs between the two (12 mm vs 10 mm), which can influence sound depth, bass response, and overall audio clarity. In general, both options are suitable for everyday use including music, calls, travel, and work-from-home scenarios. Skullcandy Sesh ANC True Wireless Earbuds and Beyerdynamic AMIRON 300 are well-known options in the wireless headphone segment, offering a balance of audio quality, battery performance, and smart features. Skullcandy Sesh ANC True Wireless Earbuds uses Bluetooth 5.2 while Beyerdynamic AMIRON 300 supports Bluetooth 5.3, which can impact connectivity stability and efficiency. Battery life varies between the two (ANC ON 32, ANC OFF 46 Hours vs 10 / 28 / 38 Hours), which affects how long you can use them on a single charge. Skullcandy Sesh ANC True Wireless Earbuds and Beyerdynamic AMIRON 300 offer different noise cancellation capabilities (Active NC vs Active Noise Cancellation), which can impact how effectively they block external noise.

Verdict: Both models are competitive, and your decision should be based on your usage needs and preferred features.